A small clinical trial from USC provides important clues about this discrepancy, in the first Alzheimer’s prevention study to compare levels of omega-3s in the blood with those in the central nervous system. The findings suggest that higher doses of omega-3 supplements may be needed in order to make a difference because dramatic increases in blood levels of omega-3s are accompanied by far smaller increases within the brain. Among participants who carry a specific mutation that heightens the risk for Alzheimer’s, taking the supplements raised levels of a key fatty acid far less compared to those without the mutation.
To learn more about this publication please visit https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(20)30258-9/fulltext
