Study Spotlight: Understanding the MIND Diet Trial In this edition, we’ll delve into the intriguing findings of the MIND diet trial and explore ideas for future nutritional studies aimed at preserving cognitive function. The MIND Diet Trial: A Closer Look In the MIND diet trial, 604 individuals were studied to explore the effects of dietary …
Study Spotlight: Associations of ApoE4 status and DHA supplementation on plasma and CSF lipid profiles and entorhinal cortex thickness How does ingested DHA get into the brain? When it does, what effect does APOE4 have? These were the questions asked in a recently published study titled “Associations of APOE4 status and DHA supplementation on plasma and …
Study Spotlight: Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer’s dementia We’re excited to share a recent study that investigates how the activation of the eicosanoid lipidome differs in individuals with APOE4 and Alzheimer’s dementia. This study was a collaboration between the teams of Dr. Stan Louie and Dr. Hussein …
USC Neurology/Alzheimer’s Disease Research Center Spotlight We are excited to share with you a recent video highlighting the USC Alzheimer’s Disease Research Center’s (ADRC) cutting-edge research and patient care. The ADRC is dedicated to finding new treatments for Alzheimer’s Disease (AD) and improving the lives of those currently affected by the disease. This video features interviews with leading …
Happy New Year! We hope this message finds you well as we welcome you into the new year. One of the best ways to start off the year is by taking steps to maintain and improve our cognitive health; a healthy brain can have a significant impact on our quality of life. Alzheimer’s disease is …
In this collaboration with Artery Therapeutics, Sasan Noveir, Bilal Kerman and the team show that a peptide that makes HDL promotes the clearance of amyloid from the brain in cynomolgus monkeys. The study looked at the effects of a synthetic peptide (CS-6253) on biomarkers relevant to Alzheimer’s Disease in cynomolgus monkeys, a species that shares …
Does making new HDL particles affect Alzheimer’s disease? Read More »
The Nutrition for Dementia Prevention working group was formed in 2020 by an international group of experts to address the following paradox: observational studies reveal an association between a healthy diet or dietary components and better brain health, but clinical trials investigating healthy diets or supplements have not shown convincing clinical benefit. Over the past …
Proceedings of the Nutrition for Dementia Prevention Working Group Symposium Read More »
Abstract INTRODUCTION: It is unknown whether rates of cognitive decline differ between older women and men with type 2 diabetes (T2D) and overweight or obesity. METHODS: Two to four cognitive assessments were obtained across up to 10 years from 2799 adults (mean age 68 years; 62% women) with T2D who had been enrolled in a …
As you probably know, there are no effective treatments that can modify or slow down the progression of Alzheimer’s Disease. It is necessary to have a new understanding of the key elements that are driving pathology and key targets that can be investigated to stop this disease and its effect on our aging population. Publication: Calcium-dependent …
Abstract Background: Sex may be an important modifier of brain health in response to risk factors. We compared brain structure and function of older overweight and obese women and men with type 2 diabetes mellitus. Methods: Cross-sectional cognitive assessments and magnetic resonance images were obtained in 224 women and 95 men (mean age 69 years) with histories …